The Nashua National Fish Hatchery, located in Nashua, New Hampshire, was established in 1898. It is a working part of the Eastern New England Fisheries Resource Complex and is one of 11 national fish hatcheries in the Northeast Region and one of 70 in the National Fish Hatchery System (NFHS). The NFHS works to conserve rare imperiled species, as well as common game fish to strengthen ecosystems and economies.

Work at the hatchery supports Atlantic salmon, American shad and other aquatic species restoration efforts in the Merrimack and other New England rivers. The station provides Atlantic salmon eggs for fry release programs and retired broodstock for Atlantic salmon recreational fisheries.

American shad eggs are obtained from adult shad returning to the Merrimack River. The eggs are incubated at the hatchery, and once they hatch, the juveniles are released into sections of the Merrimack River and other New England rivers.

The Nashua National Fish Hatchery also hosts school students, scouting troops and other civic organizations for educational tours and programs at the station.