GnRH IIa Chicken Gonadotropin – Releasing Hormone II analog

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GnRH IIa is a synthetic peptide analogue of chicken gonadotropin-releasing hormone (cGnRH IIa). It is presented as a dry powder to be resuspended in saline solution for intraperitoneal (IP) injection and is only available for purchase through AquaTactics Fish Health. The use of hormones to induce spawning in fish is critical to the success of many aquatic programs that need hormone treatment to complete final gamete maturation to ensure spawning. The primary goal of field studies conducted under INAD #13-345 is to generate data to help determine appropriate GnRH IIa treatment regimens for use as a spawning aid for female ictalurids. Fish may be treated at a dose up to 100 microgram (µg) GnRH IIa per kilogram (kg) body weight with single or multiple IP injections. Multiple injections will generally consist of a single “priming dose,” followed by a single “resolving dose.” Adherence to a 1-day Investigational withdrawal period is required for all fish treated with GnRH IIa under this INAD. Note: if MS222 or Aqui-S 20E is used at time of injection, then the withdrawal time for the anesthetic must be followed. To participate in the INAD Program for GnRH IIa visit the data collecting site.

Please read the Study Protocol prior to any treatments. It contains the protocol, MSDS, and a copy of the forms to be used as a guide for collecting data that will be entered into the online INAD database. The FDA authorization letter(s) for this INAD is currently only available by emailing Bonnie Johnson.