Drug Research Information Bulletin - Calculations to Determine the Amount of Terramycin® 200 for Fish (Oxytetracycline Dihydrate) Type A Medicated Article to Add to Fish Feed

Terramycin® 200 for Fish (Oxytetracycline Dihydrate) Type A Medicated Article (TM200; Phibro Animal Health, Ridgefield Park, NJ) contains 200 g active oxytetracycline (OTC)/lb and is approved for use in U.S. aquaculture for the following indications: (1) control of ulcer disease (causative agent, Hemophilus piscium), furunculosis (causative agent, Aeromonas salmonicida), bacterial hemorrhagic septicemia (causative agent, A. liquefaciens), and pseudomonas disease (causative agent, Pseudomonas spp.) in salmonids; (2) control of mortality in freshwater-reared salmonids due to coldwater disease (causative agent, Flavobacterium psychrophilum); (3) control of mortality in all freshwater-reared Oncorhynchus mykiss due to columnaris disease (causative agent, F. columnare); (4) control of hemorrhagic septicemia and pseudomonas disease in catfish; (5) marking of skeletal tissue in Pacific salmon; and (6) control of gaffkemia (causative agent, Aerococcus viridans) in lobster.