
Refuge lands are open for general use from ½ hour before legal sunrise to ½ hour after legal sunset.
- Hiking is allowed on refuge roads and trails, unless otherwise posted.
- ATVs and UTVs are not allowed on the refuge.
- Dogs must be on a leash.
- Berry and mushroom gathering is allowed for personal consumption only, not for resale or other commercial use.
- Collecting shed deer antlers is not allowed.
- Camping or fires are not permitted.
- The taking of any mussel, clam, crayfish, leach, frog and turtle species is prohibited.
- Fishing is allowed by boat ONLY in Bryants Creek and the Mississippi River and its side-channels. Gas boat motors are prohibited on the refuge with the exception of Bryants Creek.
- Hunting is allowed according to regulations in the refuge hunting and fishing brochure, and state regulations.
- Firearms are allowed only during authorized hunting activities. They must be unloaded and either dismantled or cased when transporting on refuge roads or waters, unless in compliance with state concealed carry regulations. Target shooting or any non-hunting discharge of firearms is prohibited.
- Trapping of muskrat, beaver and raccoon is permitted on refuge land, but special regulations apply and a refuge special use permit is required.
- Possession of alcoholic beverages is prohibited.
For more information on refuge specific rules and policies
| Activity | Unit | Season Dates | Species - Bag Limit | Regulation |
| Migratory Bird Hunting | West Unit | Closed to migratory bird hunting. | None | None |
| Riverside Unit*** | Open in accordance with Missouri state seasons and regulations. See additional special regulations. | Crow, dove, dark& light geese, ducks, teal, coot, rail, snipe and woodcock. State bag limit | Within state season dates, hunting can occur only between March16 and October 14. | |
| McCoy Island Unit | Open in accordance with Illinois state seasons and regulations. | Crow, dove (mourning and white-winged), dark& light geese, ducks, teal, coot, rail, snipe and woodcock. State bag limit. | None | |
| Upland Game | West Unit | Closed to upland game hunting. | None | None |
| Riverside Unit*** | Open in accordance with Missouri state seasons and regulations. See additional special regulations. | Badger, bobcat, coyote, fox, opossum, pheasant, quail, rabbit, raccoon, squirrel, skunk and woodchuck/groundhog. State bag limit. | Within state season dates, hunting can occur only between March16 and October 14. | |
| McCoy Island Unit | Open in accordance with Illinois state seasons and regulations. | Bobcat, coyote, fox, opossum, Hungarian partridge, pheasant, pigeon, quail, rabbit, raccoon, skunk, squirrel, unprotected dove (Eurasian-collared and ringed turtle dove) and woodchuck/groundhog. State bag limit. | None | |
| Turkey Hunting | West Unit | Closed to turkey hunting. | None | None |
| Riverside Unit*** | Open in accordance with Missouri state seasons and regulations. See additional special regulations. | State turkey bag limit. | Within state season dates, hunting can occur only between March16 and October 14 | |
| McCoy Island Unit | Open in accordance with Illinois state seasons and regulations. | State turkey bag limit. | None | |
| Deer Hunting | West Unit | Allowed ONLY during Missouri state-managed hunts | Bag deer limit per state managed hunt regulations. | Requires a refuge permit |
| Riverside Unit | Allowed ONLY during Missouri state-managed hunts | Bag deer limit per state managed hunt regulations. | Requires a refuge permit | |
| McCoy Island Unit | Open in accordance with Illinois state seasons and regulations. | State deer bag limit. | Feral hogs may be taken only while attempting to fill an unfilled deer hunt tag. | |
| Trapping | West Unit and Riverside Units | Open in accordance with Missouri state seasons and regulations. See additional special regulations. | Muskrat, beaver and raccoon. State bag limit. | Special regulations apply and require a Refuge Special Use Permit. |
| McCoy Island Unit | Closed | None | None |

