Drug Research Information Bulletin - Stability of Eugenol in Solutions of AQUI-S®20E

AQUI-S®20E (10% eugenol) is a fish sedative developed by AQUI-S New Zealand, Ltd. (Lower Hutt, NZ), and it has become the lead candidate for approval in the U.S. as an immediate-release sedative. AQUI-S NZL is working with a variety of public-sector data-generating partners to establish that the product is efficacious; safe to fish, humans, and the environment; and can be manufactured consistently according to FDA criteria. Research study protocols have been developed to generate efficacy and target animal safety data in support of a U.S. approval. Such studies require the concentration of exposure baths be analytically verified to confirm the actual sedative concentration tested is acceptably close to the target concentration.

Author(s)
Jim Bowker
Publication date
Type of document
Fact Sheet
Program
A fish with a reddish tone body with black spots on upper part of body, this side view of a Chinook salmon shows the salmon swimming right above a gravel riverbed.
Healthy fisheries are core to the conservation work of the U.S. Fish and Wildlife Service. We are working with partners to protect and enhance the health of fish and other aquatic animals in aquaculture and in the wild.
A man is fishing in a boat with three young girls. The kids are excitedly pulling a fish out of the water.
Healthy fisheries and waters are the foundation of America’s outdoor traditions and give us the freedom to fish, boat, and enjoy the benefits of outdoor recreation. The Fish and Aquatic Conservation programs work with states, tribes, and communities to provide a comprehensive approach to freshwater...
Subject tags
Fishes
Research
Aquaculture
Animal health