AQUI-S®20E (10% eugenol) is a fish sedative developed by AQUI-S New Zealand, Ltd. (Lower Hutt, NZ), and it has become the lead candidate for approval in the U.S. as an immediate-release sedative. AQUI-S NZL is working with a variety of public-sector data-generating partners to establish that the product is efficacious; safe to fish, humans, and the environment; and can be manufactured consistently according to FDA criteria. Research study protocols have been developed to generate efficacy and target animal safety data in support of a U.S. approval. Such studies require the concentration of exposure baths be analytically verified to confirm the actual sedative concentration tested is acceptably close to the target concentration.
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