OvaRH® is a synthetic peptide analogue of salmon gonadotropin-releasing hormone (sGnRHa). It is presented as a soluble powder for dissolution in saline as an injection either as an intraperitoneal (IP) or intramuscular (IM) injection. OvaRH® is only available for purchase through Syndel USA. The use of hormones to induce spawning in fish is critical to the success of many aquatic programs that needs hormone treatment to complete final gamete maturation to ensure spawning. The primary goal of field studies conducted under INAD #12-186 is to generate data to help determine appropriate OvaRH® treatment regimens for inducing gamete maturation in a variety of freshwater and marine finfish. Fish may be treated up to 50 microgram (µg) OvaRH® per kilogram body weight with single or multiple injections. Multiple injections will generally consist of a single “priming dose,” followed by a single “resolving dose.” A 14 day Investigational withdrawal period has been set for treated fish. To participate in the INAD Program for OvaRH® visit the data collecting site.
Please read the Study Protocol prior to any treatments. It contains the protocol, MSDS, and a copy of the forms to be used as a guide for collecting data that will be entered into the online INAD database. The FDA authorization letter(s) for this INAD is currently only available by emailing Bonnie Johnson.
INAD objective/purpose: Collect supportive and pivotal data needed to establish the effectiveness of sGnRHa/OvaRH® to induce gamete maturation in a variety of fish species.
OvaRH®; Salmon Gonadotropin - Releasing Hormone analogue (sGnRHa)
1441 W Smith Rd,
Ferndale, WA 98248 USA
Target pathogen(s): Not Applicable
Method of administration: IM or IP injection
Investigational Withdrawal period:
Required test parameters:
Limitations or restrictions on use of drug:
Required INAD fee: $700/facility/year
AADAP Contact Information:
Ms. Bonnie Johnson, FWS-AADAP