Oxytetracycline hydrochloride (OTIMM) is an aquaculture premix containing oxytetracycline hydrochloride and is available through Pharmagate. OTIMM is available for purchase through many local farm & ranch stores or veterinarian supply outlets. The primary goal of field studies conducted under INAD #9033 is to evaluate the efficacy of OTIMM for controlling mortality in a variety of freshwater and marine finfish species for bacterial diseases. Immersion therapy is often the only option when treating young fish not yet accustomed to feeding on man-made fish diets. Reluctance or refusal of young fish to consume such feed excludes medicated feed treatment as a therapy option. The treatment regimen is a 1-h static-bath or flow-through treatment at a dose of 20 mg OTC/L, and fish may be treated up to 4 consecutive days. The Investigational withdrawal period is 21 days for fish treated a single treatment and 60 days for multiple treatments. To participate in the INAD Program for OTIMM visit the data collecting site.
Please read the Study Protocol prior to any treatments. It contains the protocol, MSDS, and a copy of the forms to be used as a guide for collecting data that will be entered into the online INAD database. The FDA authorization letter(s) for this INAD is currently only available by emailing Bonnie Johnson.
INAD objective/purpose: Collect supportive and pivotal data needed to establish the effectiveness of oxytetracycline (OTC) immersion therapy to control mortality caused by certain bacterial diseases.
Pennox 343® (oxytetracycline hydrochloride)
Drug Source: Pharmagate (often available from your local farm & ranch store, veterinary supply outlet, etc.)
14040 Industrial Road
Omaha, Nebraska 68144
Mr. Doug Rupp
Target pathogen(s): Bacterial pathogens susceptible to oxytetracycline.
Method of administration: Immersion treatment
Investigational Withdrawal period:
Required test parameters:
Limitations or restrictions on use of drug:
Required INAD fee: $700/facility/year
AADAP Contact Information:
Ms. Bonnie Johnson, FWS-AADAP