Fish and Aquatic Conservation


Chloramine-T INAD #9321

Juvenile muskellunge. Muskellunge inhabit clear vegetated lakes, quiet pools, and the backwaters of creeks and small to large rivers. Credit: Brett Billings/USFWS

Summary

Chloramine-T (CLT) is a powder that is applied as an immersion bath treatment. CLT is only available for purchase through Syndel USA or B.L. Mitchell, Inc. The primary goal of field studies conducted under INAD #9321 is to evaluate the efficacy of CLT for controlling mortality in a variety of freshwater fish species for bacterial diseases not currently listed on the approved label. INAD use is for non-labeled use only and all labeled use must follow the approved label. The treatment regimen is a 1-h static-bath or flow-through treatment at a dose of 10, 15, or 20 mg/L CLT, and fish may be treated 1 – 3 times on alternate or consecutive days. The Investigational withdrawal period is zero days for fish treated up to 3 days. To participate in the INAD Program for CLT visit the data collecting site.

Please read the Study Protocol prior to any treatments. It contains the protocol, MSDS, and a copy of the forms to be used as a guide for collecting data that will be entered into the online INAD database. The FDA authorization letter(s) for this INAD is currently only available by emailing Bonnie Johnson .


INAD objective/purpose: Collect supportive and pivotal data needed to establish the effectiveness of Chloramine-T to control mortality caused by certain bacterial diseases.

Drug Name
Chloramine-T (Halamid® Aqua)

Drug Source
Syndel USA
1441 W Smith Rd,
Ferndale, WA 98248 USA

Jason Montgomery
Phone: 800-283-5292
Fax: 360-384-0270
email: jasonm@syndel.com
Website: www.syndel.com

Drug Name
Chloramine-T (Actamide)

Drug Source
B.L. Mitchell, Inc.
1774 E Azalea Dr.
Greenville, MS 38701-7505

Martin Mitchell
Phone: 662-686-9002
Fax: 662-686-9020
email: biologist@tecinfo.com
Website: http://www.blmitchell.com

Target pathogen(s): External flavobacteriosis; exclusive of already approved claims.

Method of administration: Immersion: flow-through or standing bath treatment

Treatment dosage:

  • 10 - 20 milligram (mg) per Liter

Treatment regimen:

  • 60 minutes per day for up to 3 days.
  • 60 minutes per day once a week for preventative measures

Investigational Withdrawal period:

  • No Investigational withdrawal period for fish treated up to 3 days.

Required test parameters:

  • Investigator must collect mortality data throughout the 5 day pre-treatment, treatment, and 10 day post-treatment periods. Investigator should also report general fish behavior and any adverse effects relating to treatment.

Limitations or restrictions on use of drug:

  • Not for use for existing FDA-approved claims for chloramine-T.
  • Unless otherwise stated in your NPDES permit, the effluent discharge limit for this drug is 0.1 ppm.
  • Not for use on fish in culture systems with no outflows.
  • Investigator must follow all instructions in the Study Protocol for INAD 9321 regarding drug acquisition and handling, fish treatment and disposition, and data reporting requiremen
  • Drug discharge must be in compliance with local NPDES permitting requirements.

Required INAD fee: $700/facility/year

AADAP Contact Information:
Ms. Bonnie Johnson, FWS-AADAP
Phone: 406-994-9905
Fax: 406-582-0242
email: bonnie_johnson@fws.gov