Fish and Aquatic Conservation


AQUI-S®20E INAD #11-741

Largemouth bass in coontail.
Credit: Ryan Hagerty, /USFWS

Summary

Aqui-S®20E is a liquid containing 10% eugenol that is applied as an immersion bath treatment. Aqui-S®20E is only available for purchase through AquaTactics Fish Health / AQATAQ Vaccines. The primary goal of field studies conducted under INAD #11-741 is to evaluate the efficacy of Aqui-S®20E for use as an anesthetic/sedative in all freshwater-reared finfish, freshwater prawn, all saltwater-reared finfish, and sharks. Fish may be treated between 10 – 100 milligram (mg) eugenol per L for up to 15 minutes. Treatment duration will vary dependent upon species, water temperature, and level of sedation desired. AQUI-S® 20E should be applied as a single treatment event. Note: For sedation to handleable, a treatment dosage of 20-60 mg eugenol per L is recommended for all species. For field use, both freshwater and saltwater finfish treated with AQUI-S®20E can be released immediately back into their natural environment; for hatchery use, a 72-hour Investigational withdrawal period is required. To participate in the INAD Program for AQUI-S®20E visit the data collecting site.

Please read the Study Protocol prior to any treatments. It contains the protocol, MSDS, and a copy of the forms to be used as a guide for collecting data that will be entered into the online INAD database. The FDA authorization letter(s) for this INAD is currently only available by emailing Bonnie Johnson .


INAD objective/purpose: Collect scientific data necessary to establish the effectiveness AND safety of AQUI-S® 20E as an anesthetic/sedative in a variety of fish species under a variety of environmental conditions.

Drug Name
Aqui-S®20E

Drug Source
AquaTactics Fish Health / AQATAQ Vaccines
12015 115th Avenue NE, Suite 120
Kirkland, WA 98034

Tom Goodrich
Phone: 425-922-4208
Fax: 425-629-8095: email: tomg@aquatactics.com
website: http://www.aquatactics.com

Target pathogen(s): Not Applicable

Method of administration: Immersion; standing bath treatment only

Treatment dosage:

  • Note: For sedation to handleable, a treatment dosage of 20-60 mg eugenol per L is recommended for all species.

Treatment regimen:

  • Treatment duration is up to 15 minutes. Treatment duration will vary dependent upon species, water temperature, and level of sedation desired.
  • AQUI-S® 20E & AQUI-S®E should be applied as a single treatment event.

Investigational Withdrawal period:

  • 72 hours for hatchery use
  • Freshwater and marine finfish that are sedated by resource managers as part of field-based fishery management activities can be released immediately after treatment. The immediate release provision is for field use only.
  • No Investigational withdrawal period is required for fish that are not susceptible to legal harvest for a period of 72 hours post-treatment. Euthanized fish must not be sent to slaughter or be otherwise available for food.

Required test parameters:

  • Investigator must collect data documenting: 1) time to sedation; and 2) time to recovery from sedation. Investigator must also report general fish behavior and any adverse effects relating to treatment.

Limitations or restrictions on use of drug:

  • Investigator must follow all instructions in the Study Protocol for INAD 11-741 regarding drug acquisition and handling, fish treatment and disposition, and data reporting requirements.
  • Drug discharge must be in compliance with local NPDES permitting requirements.

Required INAD fee: $700/facility/year

AADAP Contact Information:
Ms. Bonnie Johnson, FWS-AADAP
Phone: 406-994-9905
Fax: 406-582-0242
email: bonnie_johnson@fws.gov