Santee National Wildlife Refuge
Southeast Region
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Hours of Operation:

Visitor Center:

8:00 am - 4:00 pm Tuesday - Friday

Refuge trails and grounds are open daily sunrise to sunset, EXCEPT on the Cuddo and Bluff Units, which are open as noted below:

October 1 - February 28 - 7:00 am - 5:00 pm

March 1 - September 30 - 6:00 am - 8:00 pm


Directions to Santee NWR:

From I-95 (North or South):
Take Hwy. 15/301 exit on North side of Lake Marion (exit 102).

From I-26 East (Charleston): approximately 1 hour: Take I-26 to I-95. Take I-95 North until you reach exit 102 (Hwy 15/301).

From I-26 West (Columbia): approximately 1 hour: Take I-26 to 301 East (towards Santee). Go approximately 16 miles to Santee, where 301 will turn onto I-95 North. Take I-95 North for approximately 4 miles to exit 102.

From Hwy. 15/301:
Follow signs to visitor Center.


Click here for larger map.

Santee Map


Santee Indian Mound & Ft. Watson


Last updated: September 17, 2014