The Science Applications Program works with all U.S. Fish and Wildlife Service programs, as well as our agency's many conservation partners, to promote and facilitate the use of the best science available to address threats to native plants, animals and their habitats. In particular, large scale issues such as climate change, invasive species and habitat fragmentation are affecting all ecosystems and thus, now more than ever, require a collaborative, science-based approach to better understand, plan and take action to address these threats.