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| Drug
Summary & History |
| Fungi belonging to three genera
(Saprolegnia, Achlya, and Dictyuchus) of the family Saprolegniacea are usually
associated with major fungal infections on fish and fish eggs. If fungal
infections are not treated, severe losses of fish and fish eggs can occur.
Although malachite green was once used extensively to control mortality
in fish and fish eggs diagnosed with fungal infections, its use in the U.S.
has been severely restricted (prohibited) since the early 1980's because
of human safety concerns. Of the many compounds that have been tested as
replacements for malachite green, formalin has emerged as the primary candidate
for approval in the U.S. to control fungal infections in fish and fish eggs.
The primary goal of field studies conducted under INAD #9103 is to generate data to help establish the efficacy of formalin as a fungicide for the treatment of cultured fish and fish eggs. Under this INAD, the three companies authorized to supply formalin to Investigators are (1) Argent Chemical Laboratories (Redmond, WA), (2) Natchez Animal Supply (Natchez, MS), and (3) Western Chemical, Inc. (Ferndale, WA). The standard dosage recommended in the Protocol to prevent or control fungus on fish and eggs is to administer formalin as a static-bath or flow-through treatment at 15 - 2000 mg/L active drug. For eggs, treat daily or every other day until hatch. For fish, treat every other day to weekly. The standard withdrawal period is 5 d. |
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