Bald eagle - Haliaeetus leucocephalus (T)
 Snail darter - Percina tanasi (T)
 Cumberland monkeyface pearly mussel - Quadrula intermedia (E)(h)
 Dromedary pearly mussel - Dromus dromas (E)(h)
 Fine-rayed pigtoe - Fusconaia cuneolus (E)(h)
 Orangefoot pimpleback - Plethobasus cooperianus (E)
 Pink mucket pearly mussel - Lampsilis abrupta (E) (=Lampsilis orbiculata)
 Rough pigtoe - Pleurobema plenum (E)(h)
 Tuberculed-blossom pearly mussel - Epioblasma torulosa torulosa (E)(h)
 Large-flowered skullcap - Scutellaria montana (E)
 Small-whorled pogonia - Isotria medeoloides (T)
White fringeless orchid - Platanthera integrilabia (C)
 Virginia spirea - Spiraea virginiana (T)